The Blog

2022-

2022-03-29 d
CONSEQUENCES IV

"VACCINES" NEITHER SAFE NOR EFFECTIVE

COPTIGATE - THE WORST DESIGN FLAW IN HUMAN HISTORY THAT IS IMPACTING YOUR HEALTH

[...] Trying to tell your body to generate proteins is hard for many reasons. One of them is the fact that when you try to run the protein information via ribosomes which process that code and generate the protein, it can be very slow or can get stuck during the process.

Luckily, scientists found a way to overcome this problem, by doing code substitution: instead of using the original genetic code to generate the protein, they changed the letters in the code so the code would be optimized. This is known as Codon Optimization.

Codons are three nucleotides; nucleotides are the building blocks of your DNA.

Here is an example of Codon Optimization:

60% of the codons were altered,

22% of the nucleotides were altered.

And yet the end result is that the ribosomes generate the same protein!

Same? Well, not so much.

In 2011 Nature Medicine magazine published an article called "Breaking the Silence". It described how codon optimization, which uses this synonymous DNA changes, can trigger disease in a number of ways.

https://doi.org/10.1038/nm1211-1536

Turns out the protein which was manufactured when codon optimization has different ways it folds and a different 3D shape, and it "could cause immunogenicity, for example, which wouldn’t be seen until late-stage clinical trials or even after approval".

"The changed form could cause immunogenicity, for example, which wouldn’t be seen until late-stage clinical trials or even after approval." (Chava Kimchi Sarfaty, FDA)

This statement relates to the NORMAL approval cycle. The COVID vaccines went via an accelerated one.

"codon optimization can lead to alterations in protein conformation and function…. and increase immunogenicity….some of these elements can … alter protein folding, and lead to changes in protein conformation and post-translational modifications.” (Vincent P. Mauro)

Protein misfolding "has been linked with neurodegeneration in Alzheimer and Parkinson disease, and many other pathologies."

pubmed.ncbi.nlm.nih.gov/28441058/

"The data confirm that protein misfolding resulting in intracellular PAO accumulation is sufficient to cause cardiomyocyte death and heart failure."

pubmed.ncbi.nlm.nih.gov/18612262/

So if it is so problematic, why do manufacturers use it? because "higher levels of protein expression are required for clinical trials and commercialization, and these expression levels can sometimes be obtained by using (codon optimization)" (Vincent P. Mauro, 2018)

Pfizer is the most aggressive in their genetic code optimization (as far as we know); just read the abstract from "BNT162b2 Vaccine: Possible Codons Misreading, Errors in Protein Synthesis and Alternative Splicing's Anomalies"

doi.org/10.22541/au.16…

(read much more)

______________________

Permission is hereby granted to any and all to copy and paste any entry on this page and convey it electronically along with its URL,
______________________